The aluminum-plastic blister packaging of medicines is also called water-in-eye packaging, the English name is “PressThroughPackage”, nebo “PTP” for short. PTP packaging is to first transport the plastic sheet to the electric heater to soften it, then place the sheet in the mold, and then fill the sheet with compressed air from the upper mold or vacuum in the lower mold to form a blister or cavity. After cooling, the drug is placed in a blister.
PTP packaging was jointly developed by the German company LAWSON MARDON SINGEN and BOSCH in the mid-1950s.

PTP packaging has great advantages: firstly, it provides patients with a dose of drug packaging, which is convenient and economical; secondly, PTP packaging has good performance of protecting drugs, high consumption efficiency, low cost, small storage space, light weight, and transportation. Convenience; thirdly, it is safe. Because the PTP package can be printed with text instructions, both the dispenser and the user can prevent the occurrence of wrong medicine.

The most common surface layer materials used in PTP aluminum-plastic blister packaging are PVC medicinal sheets and a series of composite materials which are made of metal materials by coating or compounding other functional polymer materials with PVC medicinal sheets as the base material. , These materials are mainly polyvinylidene chloride (PVDC), polychlorotrifluoroethylene (PCTFE), nylon (PA), polyethylen (PE), hliníková fólie (AL) and so on. The composite material combines the properties of a variety of materials. It not only has the fundamental properties of PVC medicinal tablets, but also has excellent properties that a single material does not have, jako např: excellent barrier properties to water vapor and oxygen, good light protection, heat sealing properties, excellent thermal stability and processability. It is gradually replacing PVC pharmaceutical tablets, and it will become one of the development directions of pharmaceutical packaging in the future.

PVC rigid sheet is the most important PTP packaging material. The selection of these material varieties can be finally determined by the pharmaceutical factory according to the advice of packaging material experts, combined with the properties of the built-in drug and relevant stability tests.

Pharmaceutical Polyvinyl Chloride (PVC) Rigid Sheet
PVC medicinal tablets are mainly made of polyvinyl chloride (PVC) resin with certain processing aids added. Through extrusion, calendering and other processing methods, a novel packaging material that meets medicinal requirements is produced. It separates each tablet, pill and capsule independently, making it the smallest packaging unit, greatly improving the accuracy and safety of using the medicine, and because the processing method is simple, the investment is small, and it is easy to form and process. The production cost of the factory has dropped significantly, and the production efficiency has been greatly improved. In the early 1990s, almost all pharmaceutical factories were willing to use the
This packaging is used to consume tablets, pills and capsules, and this trend continues to this day. PTP aluminum plastic packaging has become the first packaging method for new tablets, pills and capsules launched by more and more pharmaceutical factories and new pharmaceutical factories.

In domestic PTP packaging materials, PVC medicinal tablets account for more than 95%. The development trend of PTP aluminum plastic packaging abroad is currently dominated by PVC materials, but now there are packaging materials such as PP, PET, PS, atd., but there is a gap between the comprehensive performance and PVC, and the main thing is the appearance of the drug packaging. No new image. Proto, the packaging materials used in PTP aluminum-plastic packaging are mainly PVC materials in foreign countries, accounting for about 60%, and most of the rest are composite packaging materials, and other single packaging materials account for a small proportion. In terms of growth rate, the growth rate of composite packaging materials is 3-4 times that of single packaging materials. Proto, composite packaging materials will soon become the mainstream of PTP packaging.