Alu-Alu-Blisterverpackung für den besten medizinischen Zweck
Alu Alu blister packaging is the most premium blister packaging choice — we estimate that the cost per pack is 50 percent more than the cost per pack for regular PVC-based blister packaging. Auf der anderen Seite, users receive the finest possible protective barrier for their goods in exchange for paying a premium. Market information reveals that a considerable proportion of items packaged in an Alu Alu blister form do not require that level of impermeability; rather, packers and manufacturers are using Alu Alu as ‘belts and braces’ method to protect their products from contamination.
It is possible to nearly completely remove water vapor permeability, as well as oxygen and light intrusion, on an Alu Alu and CFF (Cold-Formed Foil) blister pack since both the base and lidding are constructed from the aluminum-based film: OPA-ALU-PVC (nylon-ALU-PVC). These foil blister packs are created using a cold-forming technique, wherein the laminate is squeezed into a mold without the use of heat, and forming pins are used to create this same product cavity in the finished product. The package is then closed with a lidding material made of aluminum.
In order to ensure efficacy and patient safety, it is critical that perhaps the Active Pharmaceutical Ingredient (API) holds steady inside the finished product until the climax of its shelf life. Thermal degradation, Oxidation, ultraviolet light, microorganisms, and hydrolysis are all potential sources of instability. Manufacturing technologies that can safeguard the API include, zum Beispiel, tabletting inert ingredients that will soak water & film coatings that will prevent moisture from accessing the core of the drug.
Packaging vendors have also recognized the need for greater protection of extremely sensitive medications. Aluminum blisters provide a virtually full barrier against moisture, hell, and air – elements that can cause drug stability to deteriorate, shelf life to be shortened, and drug administration to be inefficient.
An estimated 25 percent of pharmaceutical medications on the marketplace are sensitive to moisture and require the best possible humidity control to remain effective. Effervescent pills and high-value, high-potency pharmaceuticals are examples of products commonly packaged in alu alu blister foil specifications. Jedoch, instability determines the most efficient way to determine if a specific product needs that insulation value or not.
The recent advent of high resistance polymers, including PCTFE (Aclar) and next generations PVDC, has assisted in bridging the gap between the conventional, low-cost option to convert materials and Alu Alu, which was previously unbridgeable. It is becoming increasingly difficult to distinguish the effectiveness of packs built from these structures from Alu Alu’s, which is now the best available technology. Films made from copolymer polyesters are also noteworthy (COCs). According to the research, these films have a water vapor barrier that is approximately ten times greater than PVC and much more than twice the same PVDC-coated PVC. Jedoch, this must be weighed against the material with poor oxygen barrier qualities.
Another benefit of these superior mechanical laminates is that, when compared to Alu Alu, they reduce the size of the blister card. This is because the capacity to develop the cavity at such a tighter angle results in smaller blister chambers and a more tightly nested blister.
As a result of the cold-forming process, the flexible protective layer is stretched (and thinned) in specific locations. The depth of a film, its bridge area (or footprint), and the draught angles at which it is generated all impact how thin it becomes. For cold-forming design, the drawing ratio is the percentage of final surface area (Af) to beginning cross-sectional area (As) of the cold-formed component (Ai).
A push-through closure constructed of aluminum foil is called lid film, sometimes known as blister film. Finally, the pills and tablets produce a hygienic and clean environment. A Blister Pack makes it convenient to transport and store.
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