Medizinisches PVC (Polyvinylchlorid) und PVDC (Polyvinylidenchlorid) are both commonly used materials in the pharmaceutical industry for packaging purposes. While they have some similarities, there are significant differences between the two:

Komposition:

Medizinisches PVC: It is a thermoplastic polymer composed primarily of vinyl chloride monomers. Additional additives are incorporated to enhance its properties such as flexibility, impact resistance, und Stabilität.
PVDC: It is a thermoplastic polymer composed primarily of vinylidene chloride monomers. PVDC is a copolymer of vinylidene chloride and other monomers, enthält typischerweise einen geringen Prozentsatz an Vinylchlorid.
Barriereeigenschaften:

Medizinisches PVC: PVC bietet mäßige Barriereeigenschaften gegen Feuchtigkeit, Sauerstoff, und andere Gase. Es bietet ausreichenden Schutz für die meisten pharmazeutischen Produkte, ist jedoch möglicherweise nicht so wirksam für hochempfindliche oder feuchtigkeitsempfindliche Formulierungen.
PVDC: PVDC ist für seine hervorragenden Barriereeigenschaften bekannt. Es bietet eine außergewöhnliche Barriere gegen Feuchtigkeit, Sauerstoff, hell, und andere Gase. PVDC-beschichtete Folien oder Laminate bieten einen hervorragenden Schutz, um die Stabilität und Langlebigkeit pharmazeutischer Produkte zu gewährleisten.
Transparenz:

Medizinisches PVC: PVC is generally transparent, allowing visual inspection of the contents inside the packaging.
PVDC: PVDC films or coatings are highly transparent, providing excellent clarity and visibility of the packaged product.
Chemical Resistance:

Medizinisches PVC: PVC is resistant to many common chemicals and has good resistance to oils, fats, and alcohols. Jedoch, it may not be compatible with certain solvents or aggressive chemicals.
PVDC: PVDC exhibits high chemical resistance and is compatible with a broader range of solvents and chemicals compared to PVC.
Thermische Stabilität:

Medizinisches PVC: PVC has good thermal stability and can withstand a wide temperature range during processing and storage.
PVDC: PVDC has excellent thermal stability, allowing it to maintain its barrier properties even under high-temperature conditions.
Regulatory Considerations:

Medizinisches PVC: PVC is widely accepted and approved for pharmaceutical packaging applications. Jedoch, concerns have been raised about the potential leaching of plasticizers (z.B., DEHP) from PVC, especially in certain medical applications.
PVDC: PVDC is generally considered to be a safe and effective barrier material for pharmaceutical packaging. It is often used in applications where enhanced barrier properties are required.
It’s important to note that the specific properties and formulations of medicinal PVC and PVDC can vary depending on the manufacturer and the intended application. Regulatory guidelines and requirements may also dictate the choice of material for pharmaceutical packaging.