Aluminum foil is a metal with good corrosion resistance and can be used in a variety of scenarios. It is commonly used as a packaging material. Especially for the packaging of pharmaceutical products.

The storage of pharmaceuticals has strict performance requirements for packaging materials. Some pharmaceuticals need to be stored in a humid environment for a long time. Can pharmaceutical aluminum foil be archived in a humid environment?

Pharmaceutical aluminum foil storage in a humid environment can cause several potential problems, mainly due to the interaction of humidity with the aluminum foil and its contents. Several aspects need to be paid attention to.

1. Corrosion and degradation

Oxidation: Aluminum oxidizes when exposed to moisture. This oxidation forms aluminum oxide on the surface, which is usually protective, but will affect the integrity and appearance of the aluminum foil over time.

Corrosion: Aluminum foil corrodes in high humidity environments, especially in the presence of salt or other reactive substances. This impairs the barrier properties of the aluminum foil and may expose the pharmaceutical contents to air and pollutants.

2. Impact on pharmaceutical properties

Moisture penetration: If the aluminum foil is not laminated or coated with a protective layer, moisture may penetrate through micro-perforations or weak points. This can degrade the medicinal properties of the contents, especially if they are hygroscopic (absorb moisture from the air).

Chemical reactions: Some drugs react with moisture, resulting in reduced potency or even harmful byproducts. Protecting these drugs from moisture is critical.

3. Structural integrity

Flexibility and strength: Prolonged exposure to moisture can weaken the structural integrity of the foil. It is more likely to tear or puncture, which is problematic for maintaining a sterile environment for pharmaceutical products.

4. Package design

Coatings and laminates: High-quality pharmaceutical foil is often coated with a protective polymer or laminated with other materials, such as plastic or paper, to enhance its moisture barrier properties. These additional layers can significantly improve the foil’s performance in humid environments.

Sealing: Proper sealing techniques, such as heat sealing or the use of adhesives, can enhance a package’s resistance to moisture intrusion. Ensuring that the seal is intact is critical.

5. Storage conditions

Controlled environment: Ideally, pharmaceutical products, including those packaged in foil, should be stored in a humidity- and temperature-controlled environment. This minimizes the risk of degradation and ensures the longevity and efficacy of the drug.